Introduction

Halcinonide cream yog qhia rau qhov kev tiv tauj rau cov eczema, cov tshuaj lom zem me me, cov neeg dag dag lub ntsej muag,

Cov ntsiab lus

【Lub npe tshuaj】

Cov npe generic: Halcinonide qab zib

Hmong npe: Halcinonide qab zib

【Cov khoom xyaw】Halcinonide.

Tshuaj lom neeg npe: 16, {{17 - [}}}} Hydropregna {}}} {} {}20 - dione

Tshuaj Yeeb Nkab Qauv:

Molecular Cov Qauv: C₂₄H₃₂Txee₅

Molecular hnyav: 454.97

Profarser 【НIb tug dawb cream.
【Kev qhia】Contact eczema, atopic dermatitis, neurodermatitis, psoriasis with a small area, sclerosing atrophic lichen, lichen planus, discoid lupus erythematosus, seborrheic dermatitis (non-facial area), hypertrophic scar.

【Cov lus qhia】 10g: 10mg

【Kev sivthiab Noj tshuaj hov ntau】 Thov rau sab nraud rau sab nraud, ib zaug thaum sawv ntxov thiab ib zaug nyob rau yav tsaus ntuj txhua hnub.

【Cov kev tawm tsam】 Hauv ob peb tus neeg mob, daim tawv nqaij ntawm daim ntawv thov qhov chaw yuav muaj kev hlawv, thiab tawv ncauj thiab tawv ncauj. Ntev {-}}}}}}}, tshwj xeeb yog lub ntsej muag, Milia, cov tawv nqaij, cov tawv nqaij, cov tawv nqaij depigmentation, thiab kho kom huv. Thaum siv cov txheej txheem oclerascler, theem nrab ntawm fungal yog yuav tshwm sim hauv folds tawv nqaij. Thaum nqus tau los ntawm cov tawv nqaij hauv cov nyiaj ntau, cov kev tsis txaus siab uas yuav tshwm sim (saib phau ntawv faj seeb).

【Yam sib pauv】 Cov neeg mob ua xua rau cov tshuaj no. Thawj qhov txhab txhab mob los ntawm cov kab mob, cov kab mob fungi, kab mob, thiab cab. Qhov txhab mob txhab. Ntxau, rosacea. Kev siv cov tshuaj ntawm daim tawv muag (kev pheej hmoo ua rau kev ua rau GLAUUCOMA). Exudative daim tawv nqaij kab mob.

【Cov kev ceev faj】 {{0- cheeb tsam thiab siab}}} Txoj kev siv yuav ua rau cov menyuam yaus sib nqus thiab cov menyuam mos, suav nrog kev sib tw Cushing cov syndrome thiab kev loj hlob rov qab. Kev rho tawm sai sai yuav ua rau muaj kev tsis txaus ntseeg tshaj plaws. Yog tias tsis muaj kev ntseeg siab, tsum tsis txhob siv tshuaj thiab pom qhov ua rau. Ceev faj tias cov tshuaj tseem tshuav hauv cov quav tawv nqaij thiab cov pawm yuav nqus tau rau hauv lub cev.

【Siv rau hauv cev xeeb tub thiab cov poj niam ua haujlwm】Tsis muaj kev tshawb fawb nyob rau Teratogen ua haujlwm ntawm kev siv cov tshuaj no hauv tib neeg. Nws yuav tsum tau siv nrog kev ceev faj thaum cev xeeb tub. Thaum muaj pes tsawg tus tau nqus los ntawm daim tawv nqaij tom qab siv cov mis sab nraud, nws tuaj yeem raug kaw hauv niam mis, yog li nws yuav tsum tau siv nrog kev ceev faj thaum lub sijhawm lactation.

【Siv rau cov menyuam yaus】Nws yuav tsum tau siv rau thaj chaw me me rau lub sijhawm luv. Thaum cov tsos mob tso tawm, tsum tsis txhob siv cov tshuaj kom sai. Cov menyuam yaus hnub nyoog qis dua ib xyoos yuav tsum tsis txhob siv cov tshuaj no. Zam kev ntev - lub sij hawm thiab loj- thaj tsam kev tswj hwm.

【Siv hauv cov neeg mob laus】Tsis txhob muaj ntev - sij hawm thiab loj- thaj tsam kev tswj hwm.

【Kev sib cuam tshuam yeeb tshuaj】Tsis meej.

【Noj tshuaj tuag】Tsis meej.

【Pharmacology thiab Toxicology】

Chaw muag khoom:

1. Anti - inflammatory nyhuv: Cov khoom no yog cov tshuaj pleev, cov corticteroid muaj txiaj ntsig zoo, nrog anti {{{{{{{}} khaus, thiab vasoconscatory cuam tshuam. Raws li Triamcinolone Skeleton, 21 - hydroxyl pawg yog hloov los ntawm chlorine atom. Lub anti {- r} qhov kev txiav txim siab los ntawm vasoconstriction Test yog 360. Muaj pov thawj tias kev ntsuas ntawm vasoconstriction Test yog 360. Muaj cov txiaj ntsig zoo sib xws nrog cov txiaj ntsig zoo. The mechanism of its anti - inflammatory and anti - itching effects is to increase the reactivity of 尾 - receptors to catecholamines. Los ntawm kev ua kom ua kom cov adenylate cyclate, kev tsim cov chaw pw yog nce, thiab los ntawm inhibiting phosphodiesteresase, kev puas tsuaj ntawm chaw pw hav zoov raug txo. Raws li qhov tshwm sim, kev pom zoo ntawm kev pw hav zoov hauv cov hlwb tau nce, thiab tib lub sijhawm, tso cov tshuaj histamine yog inhibited. Cov nyhuv ntawm cov khoom no nyob rau hauv gramuloma hyperplasia hauv nas thiab nas zoo ib yam li ntawm dexamethasone. Pom los ntawm txoj kev ntawm inducing hind {{} next} Koj tus nas muag cov txiaj ntsig, thaum hydrocortisone ntawm 5 filling koob tshuaj tiv thaiv tsis muaj qhov cuam tshuam. Cov khoom no muaj qhov hnyav tseem ceeb - txo cov nyhuv rau tus thymus thiab po.

2. Xaiv cov khoom muag hluav taws xob ntawm ntau lub hlwb: Nws txo tus naj npawb ntawm t - lymphocks, inhibits neibhine ntau lawm, tiv thaiv cov kab ke ntawm vascular. Fibroblast proliferation thiab collagen synthesis, thiab inhibits sebaceous gland cell ua si.

3. Anti - proliferative nyhuv: Cov khoom no muaj anti - cov nyhuv. Nws txo cov ntawv sau RNN, yog li txo DNA synthesis thiab tseem cuam tshuam DNA kho. Raws li qhov tshwm sim, cov epidermis ua tiav nyias nyias, tshwj xeeb tshaj yog muaj kev cuam tshuam loj tshaj plaws ntawm collagen synthesis.

4. Immunosuppressive nyhuv: Cov khoom no khi rau cytoplasmic corticosteroid, ua rau cov kev tawm tsam, ua kom cov qauv ntawm "lysosomal genes" hauv cov hlwb; Nws tsim cov cleavage ntawm nuclear DNA hauv Lymphocytes, ncaj qha tua Lymphocytes.

Lom zem:

Ntsuas Toxicity Test: LD₅₀rau intramuscular txhaj hauv cov poj niam nas yog 84mg / kg, thiab hauv txiv neej nas yog 35mg / kg; tawv₅₀rau kev txhaj tshuaj tiv thaiv hauv cov txiv neej nas yog 215mg / kg; Intragastric kev tswj hwm ntawm cov tshuaj los ntawm 250 txog 1500mg / kg, tsis muaj tsiaj tuag tau pom.

Sub - Kev sim Toxicity Toxicity: lub ntsiab kev ua kom muaj kev puas tsuaj rau cov thymus thiab lymphocytes.

Tsis muaj kev tshawb fawb ntawm Teratogenicity ntawm cov yeeb yam sab nraud sab nraud ntawm cov khoom no, tab sis qhov kev siv ntawm tib neeg tsis tau muaj kev pheej hmoo siab dua cov pejxeem feem ntau.

Thaum cov khoom lag luam no tau thov cov chaw loj thiab cov qauv loj lossis los ntawm kev cuam tshuam hauv hypothalamic {}} adrenal axis (hpa axis).

【Pharmacokinetics】Ntau yam, suav nrog kev npaj ua ke, kev muaj kev ncaj ncees ntawm cov kab mob Epidermal, thiab occlusion, txiav txim siab nqus ntawm cov khoom no. Nws tuaj yeem nqus tau los ntawm cov tawv nqaij ib txwm thiab cov tawv nqaij, thiab kev nqus cov tawv nqaij hauv cov tawv nqaij lossis lwm cov kab mob ntawm cov tawv nqaij. Tom qab ua yuam kev nqus, nws cov tshuaj ntsuam yog ib yam li cov ntawv thov system. Ntawd yog, nws khi rau plasma cov protein los sib txawv ntawm daim siab, feem ntau yog ua rau lub siab, thiab qee tus kuj tau ua tiav los ntawm cov kua tsib.

【Chaw ntim khoom】 Cia rau hauv lub thawv ntim khoom ntim rau hauv qhov chaw txias (tsis yog tshaj 20 degree).

【Ntim】 Ntim Ntim Hauv Cov Tshuaj Txhuas Cream Noob Hmab. Txhua tus raj muaj 10G, thiab txhua lub thawv muaj 1 lub raj.

【Hnub tas sij hawm】 36 lub hlis